The (JFCR) is a

non-profit A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in co ...

cancer research Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and ...

organization based in

Ariake, Tokyo is a district in Kōtō, Tokyo, Japan. It is best known as the region adjacent to and directly east of Odaiba. Ariake is subdivided into four Japanese addressing system, ''chome'' and comprises part of the Tokyo Bay Landfill No. 10 and Tokyo Rink ...

. The JFCR was founded in 1908 as the first Japanese organization specializing in cancer by Katsusaburō Yamagiwa and his supporters. The Cancer Institute and its attached hospital of JFCR were set up in 1934. The JFCR became a full member of the

Union for International Cancer Control The Union for International Cancer Control (previously named International Union Against Cancer) or UICC is a non-governmental organisation with some 1,180 member organisations in more than 170 countries. UICC was founded in 1933 and is based i ...

in 1968.Japanese Foundation for Cancer Research (JFCR)
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Research

The Cancer Institute of JFCR is one of the leading medical and biological research institutes in Japan. When the American journal ''Science'' published a special feature on science in Japan in 1992, the institute was described as one of the most productive and most cited institutions in the world at the time. The research at the Institute covers a wide variety of biomedical fields, including biochemistry, cell biology, pathology, carcinogenesis, genomics, system biology, and biomedical engineering. Achievements include the following. *1979:

Tadatsugu Taniguchi is a Japanese immunologist known for his pioneer research on Interferons and Interferon regulatory factors. Contribution Taniguchi's work is mostly focused on immunity and oncogenesis, in particular on the mechanisms of signal transduction ...

isolated

interferon Interferons (IFNs, ) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten the ...

gene. *1983: Mitsuaki Yoshida identified the molecular structure of

human T-lymphotropic virus 1 Human T-cell lymphotropic virus type 1 or human T-lymphotropic virus (HTLV-I), also called the adult T-cell lymphoma virus type 1, is a retrovirus of the human T-lymphotropic virus (HTLV) family that has been implicated in several kinds of diseas ...

responsible for

adult T-cell leukemia/lymphoma Adult T-cell leukemia/lymphoma (ATL or ATLL) is a rare cancer of the immune system's T-cells caused by human T cell leukemia/lymphotropic virus type 1 (HTLV-1). All ATL cells contain integrated HTLV-1 provirus further supporting that causal role o ...

. *1992: Yusuke Nakamura isolated the

tumor suppressor gene A tumor suppressor gene (TSG), or anti-oncogene, is a gene that regulates a cell during cell division and replication. If the cell grows uncontrollably, it will result in cancer. When a tumor suppressor gene is mutated, it results in a loss or red ...

APC responsible for

familial adenomatous polyposis Familial adenomatous polyposis (FAP) is an autosomal dominant inherited condition in which numerous Adenomatous polyps, adenomatous Colorectal polyp, polyps form mainly in the epithelium of the colon (anatomy), large intestine. While these polyps s ...

Hospital

The Cancer Institute Hospital of JFCR was established in 1934 as Japan's only specialized cancer hospital, with just 29 beds, and the first director was

Ryukichi Inada was a Japanese physician, a prominent academic, and bacteriologist researcher. He was the discoverer of the Weil's disease pathogen. In addition to his life's work in early 20th-century Japanese medical education, he was a pioneer in Japanese ...

. The Hospital now has approximately 700 beds, and in fiscal 2011 it treated 61,324 outpatients and 9,690 inpatients.JFCR official Brochure. page 3
/ref> Clinics and departments include Thoracic Center (Thoracic Medical Oncology and Surgical Oncology), Gastroenterology Center (Gastroenterological Internal Medicine and Surgery), Breast Oncology Center (Breast Medical Oncology and Surgical Oncology), Gynecological Oncology, Head and Neck Oncology, Orthopedic Oncology, Genitourinary Oncology, Hematology Oncology, Medical Oncology, Sarcoma Center, Palliative Therapy, General Medicine, Anesthesiology/Pain Service, Psycho-Oncology, Plastic and Reconstructive Surgery, Ophthalmology, Infectious Disease, Chinese Herbal Medicine, Dentistry, Radiation Oncology, Diagnostic Radiology, Endoscopy, Comprehensive Medical Oncology, Clinical Genetic Oncology, and Cancer Screening Center.

Notable scientists and other people from JFCR

*Mataro Nagayo, pathologist * Takaoki Sasaki, oncologist *Masaru Kuru, surgeon *

Tomizo Yoshida was a prominent Japanese pathologist, famous for discovering the Yoshida sarcoma. In addition, he is known for demonstrating the chemical-induced hepatocarcinogenesis in rats with his mentor Takaoki Sasaki. Yoshida received the Imperial Prize ...

, discoverer of Yoshida Sarcoma *

Takashi Sugimura was a Japanese biochemist, famous for research on chemical carcinogens. He received the Japan Prize for the contribution to establishment of fundamental concept on causes of cancer. He was elected as President of the Japan Academy on October 1 ...

, biochemist *

Masahito, Prince Hitachi is a member of the Imperial House of Japan and the younger brother of Emperor emeritus Akihito. He is the second son and sixth born child of Emperor Shōwa and Empress Kōjun and is third in line to the Chrysanthemum Throne. Nobody follow ...

, cancer researcher and honorary president *

Kikuko, Princess Takamatsu , born , was a member of the Japanese Imperial Family. The Princess was married to Prince Takamatsu, the third son of Emperor Taishō and Empress Teimei. She was, therefore, a sister-in-law of Emperor Shōwa and an aunt-in-law of the following e ...

, sponsor for JFCR

References

External links

* {{authority control 1908 establishments in Japan Biomedical research foundations Foundations based in Japan Cancer organizations based in Japan Organizations established in 1908 Medical research institutes in Japan Buildings and structures in Koto, Tokyo

Research

Hospital

Notable scientists and other people from JFCR

See also

References

External links